Warning: require_once(D:\Sites\Single58\andresisaza\webroot\web\includes\defines.php) [function.require-once]: failed to open stream: No such file or directory in D:\Sites\Single58\andresisaza\webroot\web\index.php on line 21

Fatal error: require_once() [function.require]: Failed opening required 'D:\Sites\Single58\andresisaza\webroot\web\includes\defines.php' (include_path='.;.\;C:\php\PEAR') in D:\Sites\Single58\andresisaza\webroot\web\index.php on line 21